TLDR PRIDE syndrome includes skin and hair issues from cancer treatment with EGFR inhibitors.
The PRIDE syndrome, associated with the use of Epidermal Growth Factor Receptor (EGFR) inhibitors, encompassed a range of dermatological side effects including papulopustules, paronychia, regulatory abnormalities of hair growth, itching, and dryness. The study highlighted the need for awareness and management of these adverse effects in patients undergoing cancer treatment with EGFR inhibitors. The authors, M.E. Lacouture and S.E. Lai, from the Cancer Skin Care Program and SERIES Clinic at Northwestern University, emphasized the importance of dermatological care in improving the quality of life for these patients.
169 citations,
September 2002 in “British journal of dermatology/British journal of dermatology, Supplement” ZD1839 (Iressa) causes skin and hair side effects, treatable with tretinoin cream and minocycline.
1 citations,
January 2023 in “Przegląd Dermatologiczny” A man's severe skin reaction from cancer treatment improved with early diagnosis and proper medication.
19 citations,
October 2011 in “Clinics in Dermatology” New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.
61 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hair usually grows back 1-3 months after treatment for anagen effluvium, and children with Loose Anagen Hair Syndrome often improve by adolescence.
16 citations,
February 2019 in “Pediatric Blood & Cancer” Most children with CNS tumors on targeted therapy had skin reactions, which were generally treatable without stopping the therapy.
68 citations,
January 2014 in “Dermatology research and practice” Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.
