PRIDE Syndrome Associated With Panitumumab Treatment – Case Report and Literature Review

January 2023 in “ Przegląd Dermatologiczny ”

Magalena Pałdyna, Karolina Rutkowska, Ewelina Biało-Wójcicka

PRIDE syndrome panitumumab epidermal growth factor receptor inhibitor rash abnormal hair growth itching dryness doxycycline systemic glucocorticosteroids EGFR inhibitor steroids

TLDR A man's severe skin reaction from cancer treatment improved with early diagnosis and proper medication.

A 64-year-old man with advanced colorectal cancer experienced a severe skin reaction known as PRIDE syndrome (characterized by a rash, abnormal hair growth, itching, and dryness) after treatment with panitumumab, an epidermal growth factor receptor inhibitor. Accompanying symptoms included hypomagnesemia, hyperglycemia, and elevated glycated hemoglobin levels. The introduction of doxycycline and systemic glucocorticosteroids led to an improvement in his condition. This case highlights the importance of early diagnosis and treatment of cutaneous side effects from cancer therapy to enhance patient quality of life and allow the continuation of cancer treatment.

View this study on termedia.pl →

Discuss this study in the Community →

Similar Research

5 / 1000+ results

research Chemotherapy-Induced Iatrogenic Injury of Skin: New Drugs and New Concepts

19 citations, October 2011 in “Clinics in Dermatology”

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

research Cutaneous Reactions to Chemotherapeutic Drugs and Targeted Therapy for Cancer

88 citations, July 2014 in “Journal of the American Academy of Dermatology”

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

research Non-Rash Skin Toxicities Associated with Novel Targeted Therapies

28 citations, December 2006 in “Clinical lung cancer”

Early recognition and management of skin side effects from new cancer therapies can prevent treatment delays.

Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

research Clinical Management of Cutaneous Adverse Events in Patients on Targeted Anticancer Therapies and Immunotherapies: A National Consensus Statement by the Spanish Academy of Dermatology and Venereology and the Spanish Society of Medical Oncology

26 citations, October 2018 in “Clinical & Translational Oncology”

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

research Eyelash Trichomegaly: Review of Congenital, Acquired, and Drug-Associated Etiologies for Elongation of the Eyelashes

24 citations, May 2012 in “International Journal of Dermatology”

The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.

PRIDE Syndrome Associated With Panitumumab Treatment – Case Report and Literature Review

Related Community Posts Join

community 5 month results on natural protocol, i made a post after 3 mont of treatment wich you can find in my profile. I used different massages(detumescence therapy, wooden brush, tom hagerty exercises)vitamins(d3,fish oil, biotin,msm, magnesium) drank green tea and ate pumpkin seeds( reduces dht)

community First people receive Pyrilutamide March 19th 2022!

community Yes, most models are absolutely on finasteride

community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

community Tried everything, regressed further. Started fin, regrowth incoming! M45

community This sub in a nutshell when it comes to medicine. Oral Minoxidil isn’t that bad