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Glossary Paronychia

infection around nails causing redness, swelling, and pain

Paronychia is an infection of the skin around the nails, typically caused by bacteria or fungi. It leads to redness, swelling, and pain around the nail, and in some cases, pus may form. This condition can be acute, developing rapidly, or chronic, persisting for weeks or longer, often due to repeated exposure to moisture or irritants.

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Research

5 / 356 results

research The PRIDE (Papulopustules and/or paronychia, Regulatory abnormalities of hair growth, Itching, and Dryness due to Epidermal growth factor receptor inhibitors) syndrome

90 citations , August 2006 in “British Journal of Dermatology”

This paper describes the PRIDE syndrome associated with epidermal growth factor receptor inhibitors but reports no new clinical results.

PRIDE Complex: Papulopustules, Paronychia, Hair Growth Abnormalities, Itching, and Dryness Due to EGFR Inhibitors

research PRIDE Complex (Papulopustules and/or Paronychia, Regulatory Abnormalities of Hair Growth, Itching, Dryness Due to EGFR Inhibitors)

August 2025 in “JEADV Clinical Practice”

This case report describes the management of PRIDE complex, a skin and hair condition associated with EGFR inhibitor treatment like cetuximab, emphasizing that it does not require stopping the medication.

research Dacomitinib-Induced Paronychia Associated With PRIDE Syndrome in a Patient With Non-Small Cell Lung Cancer

June 2025 in “Cureus”

This case study documents a 55-year-old male with advanced NSCLC who experienced toe-predominant paronychia and a papulopustular rash following dacomitinib treatment, with the causality tools indicating a "probable" link, yet the therapy continued successfully without dosage alteration.