Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development

    January 2012 in “ ˜The œjournal of investigative dermatology/Journal of investigative dermatology ”
    Sylvie Lefebvre, Ingrid Fliniaux, Pascal Schneider, Marja L. Mikkola
    Studysummary This study identified chemokine receptor ligands cxcl10 and cxcl11 as new hair-specific transcriptional targets of the Eda pathway, suggesting chemokine signaling plays a role in primary hair follicle patterning.
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    Research cited in this study 12

    1. Keratinocyte-Specific Ablation of the NF-κB Regulatory Protein A20 (TNFAIP3) Reveals a Role in the Control of Epidermal Homeostasis Cell death and differentiation · 2011
    2. Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    3. Epidermal Patterning and Induction of Different Hair Types During Mouse Embryonic Development Birth defects research · 2009
    4. The Disruption of Sox21-Mediated Hair Shaft Cuticle Differentiation Causes Cyclic Alopecia in Mice Proceedings of the National Academy of Sciences · 2009
    5. The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles Differentiation · 2009
    6. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    7. TNF Superfamily in Skin Appendage Development Cytokine & growth factor reviews · 2008
    8. Identification of Dkk4 as a Target of Eda-A1/Edar Pathway Reveals an Unexpected Role of Ectodysplasin as Inhibitor of Wnt Signaling in Ectodermal Placodes Developmental biology · 2008
    9. Scratching the Surface of Skin Development Nature · 2007
    10. Integument Pattern Formation Involves Genetic and Epigenetic Controls: Feather Arrays Simulated by Digital Hormone Models ˜The œInternational journal of developmental biology · 2004
    11. Stimulation of Ectodermal Organ Development by Ectodysplasin-A1 Developmental Biology · 2003
    12. Intercellular Adhesion Molecule-1 and Hair Follicle Regression Journal of histochemistry and cytochemistry/˜The œjournal of histochemistry and cytochemistry · 2000

    Related research 1

    1. Suppression of Hair Follicle Development Inhibits Induction of Sonic Hedgehog, Patched, and Patched-2 in Hair Germs in Mice Archives of Dermatological Research · 2001