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GlossaryChemokine Receptor

protein on cell surface that binds signaling molecules called chemokines

A chemokine receptor is a type of protein found on the surface of certain cells that binds to chemokines, which are signaling molecules. This interaction helps direct the movement of immune cells to sites of inflammation, infection, or injury. Chemokine receptors play a crucial role in the immune response and are also involved in various diseases, including cancer and autoimmune disorders.

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research Chemokine Receptor CCR5 as a Novel Target for the Treatment of Alopecia Areata

August 2016 in “Journal of Investigative Dermatology”

Blocking the CCR5 receptor may be a new way to treat hair loss from alopecia areata.

research The Chemokine SDF-1/CXCL12 Regulates the Migration of Melanocyte Progenitors in Mouse Hair Follicles

57 citations, April 2009 in “Differentiation”

SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.

research High-Fat Diet Exacerbates Neutrophilic Folliculitis by Facilitating Sequential Chemokine Expressions by Keratinocytes and Neutrophils

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

A high-fat diet worsens neutrophilic folliculitis by increasing certain chemokines.

research Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development

48 citations, January 2012 in “The journal of investigative dermatology/Journal of investigative dermatology”

Chemokine signaling is important for hair development.

research Human Hair Follicles Can Smell: OR2AT4-Mediated Hair Growth Regulation

August 2016 in “Journal of Investigative Dermatology”

Human hair follicles have a scent receptor that can influence hair growth.

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community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 6 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.