Hair Growth Induction by the Tellurium Immunomodulator AS101: Association with Delayed Terminal Differentiation of Follicular Keratinocytes and Ras-Dependent Up-Regulation of KGF Expression

    December 2003 in “ The FASEB Journal ”
    Benjamin Sredni, Rivka Gal, Ian J. Cohen … Yona Kalechman
    Studysummary This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.
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    Research cited in this study 6

    1. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    2. Principles of Hair Cycle Control The Journal of Dermatology · 1998
    3. The Protective Role of the Immunomodulator AS101 Against Chemotherapy-Induced Alopecia: Studies on Human and Animal Models International Journal of Cancer · 1996
    4. Overexpression of Parathyroid Hormone-Related Protein in the Skin of Transgenic Mice Interferes with Hair Follicle Development Proceedings of the National Academy of Sciences · 1994
    5. Fibroblast Growth Factor and Epidermal Growth Factor in Hair Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1993
    6. Mice With a Null Mutation of the TGFα Gene Have Abnormal Skin Architecture, Wavy Hair, and Curly Whiskers and Often Develop Corneal Inflammation Cell · 1993

    Related research 2

    1. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD71 Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015
    2. Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis Cell · 2000