Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells

May 2013 in “ International Journal of Molecular Sciences ”

Shuang Liu, Huishan Zhang, Enkui Duan

epidermal development p63 mesenchymal signals Wnt/β-catenin PDGF Shh TGF-β epidermal stem cells hair follicles hair follicle stem cells ES cells iPS cells Wnt signaling platelet-derived growth factor sonic hedgehog transforming growth factor-beta embryonic stem cells induced pluripotent stem cells

Studysummary This review explores embryonic epidermal development and discusses key molecular regulators and roles of the sub-epidermal mesenchyme, but reports no new experimental results.

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research Defining BMP Functions in the Hair Follicle by Conditional Ablation of BMP Receptor IA

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