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GlossaryInduced Pluripotent Stem Cells (iPS cells)

cells reprogrammed from adult cells to an embryonic-like state

Induced Pluripotent Stem Cells (iPSCs) are a type of stem cell that scientists create by reprogramming adult cells, such as skin or blood cells, to revert to an embryonic-like state. This process allows these cells to potentially develop into any type of cell in the body, making them valuable for research, regenerative medicine, and disease modeling.

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research TGF-β Family Signaling in Stem Cells

132 citations , August 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects”

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

research Regeneration of a Bioengineered 3D Integumentary Organ System from iPS Cells

12 citations , April 2019 in “Nature protocols”

Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.

research A Human Prenatal Skin Cell Atlas Reveals Immune Cell Regulation of Skin Morphogenesis

October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Immune cells are essential for early hair and skin development and healing.

research Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in In Vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures

10 citations , August 2021 in “Frontiers in cell and developmental biology”

Scientists made structures that look like human hair follicles using stem cells, which could help grow hair without using actual human tissue.

research Hair Follicle Morphogenesis During Embryogenesis, Neogenesis, and Organogenesis

4 citations , July 2022 in “Frontiers in Cell and Developmental Biology”

The document concludes that understanding adult stem cells and their environments can help improve skin regeneration in the future.

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community Dr. Tsuji and Riken to make important announcement on their hair cloning cure on Feb 10th.

in Update 56 upvotes 5 years ago

Dr. Tsuji and Riken announced a hair cloning cure with a 98.9% success rate, expected to be released in 10 years. Users expressed hope and skepticism about the affordability and timeline of the treatment.

community Is there any word on when Stempsen Therapeutics and Hairclone will start phase 1 clinical trials?

in Research/Science 6 upvotes 3 years ago

Hair cloning trials by Stempsen Therapeutics and Hairclone have no updates, and it may take at least 15 years for hair cloning to be available. The conversation also mentions treatments like Minoxidil, finasteride, and RU58841.

community Prediction: Scube3 is never coming out

in Research/Science 6 upvotes 2 years ago

Scube3, a potential hair loss treatment, is unlikely to be released because it was given to a startup company, Amplifica, which may go bankrupt and fail to bring the treatment to market. Amplifica is prioritizing other treatments over Scube3, which could lead to financial loss and the end of Scube3's development.