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    Glossary Notch2

    gene involved in cell differentiation and developmental processes

    Notch2 is a gene that plays a crucial role in cell differentiation, which is the process by which cells become specialized for specific functions. It is part of the Notch signaling pathway, a fundamental communication system that cells use to control various developmental processes and maintain tissue homeostasis. Mutations in Notch2 can lead to various medical conditions, including certain types of cancer and developmental disorders.

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    Research 10 of 1000+

    1. Epidermal Notch signalling: differentiation, cancer and adhesion Current opinion in cell biology · 2008 · 253 citations
    2. Mouse notch: expression in hair follicles correlates with cell fate determination. 1993 · 150 citations
    3. The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling Development · 2011 · 134 citations
    4. Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Stem Cell Research & Therapy · 2015 · 113 citations
    5. Impaired Notch‐MKP‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology Experimental dermatology · 2013 · 112 citations
    6. Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers Development · 2000 · 109 citations
    7. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    8. Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling Developmental biology · 2008 · 84 citations
    9. Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis Journal of Investigative Dermatology · 2007 · 78 citations
    10. Melanoblasts' Proper Location and Timed Differentiation Depend on Notch/RBP-J Signaling in Postnatal Hair Follicles 2008 · 70 citations
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