research Epidermal Notch Signaling: Differentiation, Cancer, and Adhesion
Notch signalling helps skin cells differentiate and prevents tumors.
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5 / 1000+ resultsresearch Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Epidermal Notch1 Recruits RORγ+ Group 3 Innate Lymphoid Cells to Orchestrate Normal Skin Repair
Notch1 helps skin heal by attracting specific immune cells.
research Localization of Members of the Notch System and the Differentiation of Vibrissa Hair Follicles: Receptors, Ligands, and Fringe Modulators
Notch-related genes play a key role in the development and cycling of hair follicles.
research JMJD3 and NF-κB-Dependent Activation of Notch1 Gene Is Required for Keratinocyte Migration During Skin Wound Healing
JMJD3 and NF-κB activate Notch1, which is essential for skin cell movement and wound healing.
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5 / 72 resultscommunity Shoutout to Zinc pyrithione and Piroctone olamine
Zinc pyrithione and piroctone olamine are effective for reducing hair shedding, possibly more so than ketoconazole. There is a concern about zinc pyrithione shampoo interfering with minoxidil, but it's unclear if this is proven.
community Joined the Dutasteride Master Race
Dutasteride and finasteride are discussed for hair loss treatment, with users sharing experiences and debating their effectiveness and side effects. Celebrities are noted as common users, and there is debate over which treatment is superior.
community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal
This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.
community Before and After - My journey so far
A 28-year-old used oral finasteride and minoxidil, and underwent two hair transplants in Turkey, with a total of 3150 grafts, resulting in a natural-looking hairline. The first procedure cost £3300, and the second was a free touch-up, with additional costs for flights and accommodation.
community Pyrilutamide binding affinity is similar to RU
Comparing the effectiveness of RU58841, Pyrilutamide and CB-03-01 as treatments for hair loss, with people discussing different aspects such as binding affinity, time of inhibition, safety data and cost.