Search
for

    Glossary Notch2

    gene involved in cell differentiation and developmental processes

    Notch2 is a gene that plays a crucial role in cell differentiation, which is the process by which cells become specialized for specific functions. It is part of the Notch signaling pathway, a fundamental communication system that cells use to control various developmental processes and maintain tissue homeostasis. Mutations in Notch2 can lead to various medical conditions, including certain types of cancer and developmental disorders.

    Related Terms

    Research 10 of 1000+

    1. Epidermal Notch signalling: differentiation, cancer and adhesion Current opinion in cell biology · 2008 · 253 citations
    2. The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling Development · 2011 · 134 citations
    3. Impaired Notch‐MKP‐1 signalling in hidradenitis suppurativa: an approach to pathogenesis by evidence from translational biology Experimental dermatology · 2013 · 112 citations
    4. Epidermal Notch1 recruits RORγ+ group 3 innate lymphoid cells to orchestrate normal skin repair Nature Communications · 2016 · 86 citations
    5. Localisation of members of the notch system and the differentiation of vibrissa hair follicles: Receptors, ligands, and fringe modulators Developmental dynamics · 2000 · 62 citations
    6. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1 Development · 2010 · 34 citations
    7. Pleiotropic Role of Notch Signaling in Human Skin Diseases International Journal of Molecular Sciences · 2020 · 29 citations
    8. Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis Molecular Medicine Reports · 2017 · 18 citations
    9. The Notch Intracellular Domain Has an RBPj-Independent Role during Mouse Hair Follicular Development 2016 · 16 citations
    10. Keratin-6 driven ODC expression to hair follicle keratinocytes enhances stemness and tumorigenesis by negatively regulating Notch Biochemical and Biophysical Research Communications · 2014 · 8 citations
    All research results →

    Learn

    — no results

    Try a deeper search in learn →

    Community

    — no results

    Try a deeper search in community →