TLDR Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.
The study conducted comparative genome analyses on three Chinese domestic goat breeds, sequencing the genomes of 89 goats to identify unique genetic compositions and selection signals. It revealed significant genetic differences due to geographic isolation and identified specific genes under positive selection related to traits such as coat color, hair growth, and high-altitude adaptation. Notable findings included a novel SNP in FGF5 associated with long hair in Tibetan Cashmere goats and selection signals in pigmentation genes like KITLG, ASIP, and LCORL. The research provided valuable insights into the genetic basis of phenotypic traits and the evolutionary history of these breeds, emphasizing the importance of genetic diversity and selection in domestic animals.
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October 2017 in “Journal of proteomics” The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
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June 2017 in “The FEBS journal” Disabling the FGF5 gene in sheep leads to longer wool.
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December 2016 in “Scientific Reports” Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.
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July 2002 in “Journal of Investigative Dermatology” Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.
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December 2016 in “Scientific Reports” Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.
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November 2022 in “Animal Genetics” Genomic research can help improve the quality and production of natural fibers in animals.
November 2022 in “Gigascience” A specific genetic deletion in goats affects cashmere yield and thickness.
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October 2017 in “Scientific reports” Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
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November 2020 in “Frontiers in Cell and Developmental Biology” Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
