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research Comparative Genome Analyses Reveal the Unique Genetic Composition and Selection Signals Underlying the Phenotypic Characteristics of Three Chinese Domestic Goat Breeds

30 citations, November 2019 in “Genetics selection evolution”

Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

research A Conditional Multi-Trait Sequence GWAS Discovers Pleiotropic Candidate Genes and Variants for Sheep Wool, Skin Wrinkle, and Breech Cover Traits

11 citations, July 2021 in “Genetics selection evolution”

Researchers found genes and genetic variants linked to sheep wool and skin wrinkles.

research Hairless: A Nuclear Receptor Corepressor Essential for Skin Function

January 2006 in “Advances in developmental biology”

The Hairless gene is crucial for healthy skin and hair growth.

research Hairless Is a Nuclear Receptor Corepressor Essential for Skin Function

30 citations, January 2009 in “Nuclear Receptor Signaling”

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

research Characterization of Type II Rickets Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor

November 2023 in “Biomolecules”

The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.

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community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Interesting article links major MPB theories to western diet (and life-style)

in Research/Science 54 upvotes 3 days ago

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 2 weeks ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community Finasteride, dutasteride, and oral min- My experience

in Finasteride/Dutasteride 126 upvotes 3 years ago

User took Fin for 3 years, Dut for 7 months, and oral Min for 2 months without side effects. Fin stopped hair loss for 2 years, Dut maintained hair, and oral Min regrew thinning hair.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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