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GlossaryLeucine-rich repeat-containing G-protein coupled receptor

protein on cell surface involved in cell signaling

Leucine-rich repeat-containing G-protein coupled receptors (LGRs) are a type of protein found on the surface of cells that play a crucial role in cell signaling. They are involved in various biological processes, including hormone regulation and development, by transmitting signals from outside the cell to the inside. These receptors are characterized by the presence of leucine-rich repeats, which are specific sequences of amino acids that help the receptor bind to its specific ligands.

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research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

291 citations , April 2010 in “Gastroenterology”

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

research Constitutive Internalization of the Leucine-Rich G Protein-Coupled Receptor-5 (LGR5) to the Trans-Golgi Network

58 citations , February 2013 in “Journal of Biological Chemistry”

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

research Distinct Tooth Regeneration Systems Deploy a Conserved Battery of Genes

September 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Different fish use the same genes to regrow teeth.

research Effect of Flightless I Expression on Epidermal Stem Cell Niche During Wound Repair

10 citations , July 2019 in “Advances in Wound Care”

Reducing Flightless I protein improves wound healing by activating skin stem cells.

research The Role of R-Spondins and Their Receptors in Bone Metabolism

25 citations , May 2016 in “Progress in Biophysics & Molecular Biology”

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

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community 30M Experiencing Shedding After Restarting Min + Fin + Mesotherapy, Is It Too Late?

in General 168 upvotes 1 month ago

A 30-year-old is seeking advice on hair loss treatment, currently using oral minoxidil, finasteride, mesotherapy, and a supplement. They are experiencing shedding and are anxious about the effectiveness of the treatment, asking if they should continue or consider other options like topicals or microneedling.

community Indian Subcontinent specific : Fin effects

in Finasteride/Dutasteride 4 upvotes 5 years ago

Oral finasteride is recommended over topical finasteride for men in the Indian subcontinent, with no reported side effects. Minoxidil and dermarolling are also suggested, while dietary supplements and topical finasteride are deemed less effective.

community Carnitine Tartrate + Potassium chloride + Niacin

8 upvotes 11 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community Is EAA good or bad for hair? I cant find Any information about it.

in Product 1 upvotes 4 years ago

The conversation is about whether an EAA supplement affects hair health. The user lists the ingredients but does not receive a definitive answer.