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    Glossary Lgr5

    protein marker for adult stem cells in hair follicles

    Lgr5, or Leucine-rich repeat-containing G-protein coupled receptor 5, is a protein that serves as a marker for adult stem cells in various tissues, including hair follicles. It plays a crucial role in the regeneration and repair of these tissues, making it significant in studies related to hair growth and alopecia.

    Research 10 of 625

    1. Lgr5 marks cycling, yet long-lived, hair follicle stem cells Nature Genetics · 2008 · 835 citations
    2. Wnt Signaling, Lgr5, and Stem Cells in the Intestine and Skin ˜The œAmerican journal of pathology · 2009 · 326 citations
    3. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF Nature Communications · 2017 · 117 citations
    4. A slow-cycling LGR5 tumour population mediates basal cell carcinoma relapse after therapy Nature · 2018 · 105 citations
    5. NEDD4 and NEDD4L regulate Wnt signalling and intestinal stem cell priming by degrading LGR5 receptor The EMBO Journal · 2019 · 91 citations
    6. LGR5 is a Marker of Poor Prognosis in Glioblastoma and is Required for Survival of Brain Cancer Stem‐Like Cells Brain pathology · 2012 · 82 citations
    7. Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network Journal of Biological Chemistry · 2013 · 58 citations
    8. Stem cell plasticity enables hair regeneration following Lgr5+ cell loss Nature Cell Biology · 2017 · 56 citations
    9. Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures Plastic and Reconstructive Surgery · 2013 · 39 citations
    10. <i>Pten</i> loss in Lgr5<sup>+</sup> hair follicle stem cells promotes SCC development Theranostics · 2019 · 24 citations
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