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GlossaryLgr6

protein involved in hair follicle stem cell regulation

Lgr6, or Leucine-rich repeat-containing G-protein coupled receptor 6, is a protein that plays a crucial role in the regulation of stem cells in the hair follicle. It is involved in hair growth and regeneration, making it significant in studies related to hair loss and alopecia. For professionals, Lgr6 is a marker for a specific population of stem cells that can contribute to tissue repair and regeneration.

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Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

39 citations , October 2013 in “Plastic and Reconstructive Surgery”

Human alpha defensin 5 helps heal wounds, reduce bacteria, and grow hair on burned skin.

research Distinct Expression Profile of Stem Cell Markers, LGR5 and LGR6, in Basaloid Skin Tumors

9 citations , January 2017 in “Virchows Archiv”

LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.

research Lgr6+ Stem Cells and Their Progeny in Mouse Epidermis Under Regimens of Exogenous Skin Carcinogenesis, and Their Absence in Ensuing Skin Tumors

7 citations , November 2016 in “Oncotarget”

UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.

research Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells

291 citations , April 2010 in “Gastroenterology”

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

research Stem Cell Dynamics, Migration, and Plasticity During Wound Healing

211 citations , November 2018 in “Nature Cell Biology”

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

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