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    Glossary Lgr6

    protein involved in hair follicle stem cell regulation

    Lgr6, or Leucine-rich repeat-containing G-protein coupled receptor 6, is a protein that plays a crucial role in the regulation of stem cells in the hair follicle. It is involved in hair growth and regeneration, making it significant in studies related to hair loss and alopecia. For professionals, Lgr6 is a marker for a specific population of stem cells that can contribute to tissue repair and regeneration.

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    Research 30 of 291

    1. Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures Plastic and Reconstructive Surgery · 2013 · 39 citations
    2. Distinct expression profile of stem cell markers, LGR5 and LGR6, in basaloid skin tumors Virchows Archiv · 2017 · 9 citations
    3. Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors Oncotarget · 2016 · 7 citations
    4. Lgr6+ cells in the biological system during homeostasis and injury Genes & Diseases · 2025
    5. The Roles of the Lrig1- and Lgr6-Positive Stem Cells in the Skin and the Functions of the Molecular Markers That Define Them eScholarship (California Digital Library) · 2014
    6. Abstract 12: LGR6+ Epithelial Stem Cell Augmentation of Fracture Healing Plastic & Reconstructive Surgery Global Open · 2018
    7. Leucine-Rich Repeat-Containing G-Protein-Coupled Receptors as Markers of Adult Stem Cells Gastroenterology · 2010 · 291 citations
    8. Stem cell dynamics, migration and plasticity during wound healing Nature Cell Biology · 2018 · 211 citations
    9. Single-Cell Transcriptomics of Traced Epidermal and Hair Follicle Stem Cells Reveals Rapid Adaptations during Wound Healing Cell Reports · 2018 · 209 citations
    10. Epithelial stem cells and implications for wound repair Seminars in Cell & Developmental Biology · 2012 · 156 citations
    11. Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity Cell reports · 2016 · 54 citations
    12. Reflections on how wound healing-promoting effects of the hair follicle can be translated into clinical practice Experimental Dermatology · 2014 · 43 citations
    13. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    14. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    15. The role of R-spondins and their receptors in bone metabolism Progress in Biophysics & Molecular Biology · 2016 · 25 citations
    16. Stem Cells in Dermatology and Anti-aging Care of the Skin Facial Plastic Surgery Clinics of North America · 2018 · 23 citations
    17. Are fingernails a key to unlocking the puzzle of mammalian limb regeneration? Experimental Dermatology · 2016 · 10 citations
    18. Diverse cellular players orchestrate regeneration after wounding Experimental Dermatology · 2020 · 7 citations
    19. Stem Cells and their Niches Journal of Investigative Dermatology · 2013 · 1 citations
    20. Hair follicle stem cells: A new arena International Journal of Trichology · 2011 · 1 citations
    21. Skin Epidermis and Adnexa Regrowth Induced by Treatment With Artificial Dermal Template After Full-Thickness Skin Wound The International Journal of Lower Extremity Wounds · 2019 · 1 citations
    22. Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle Science · 2026
    23. Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars Australasian journal of dermatology · 2024
    24. Impact of Stem Cells on Reparative Regeneration in Abdominal and Dorsal Skin in the Rat Journal of developmental biology · 2024
    25. Distinct tooth regeneration systems deploy a conserved battery of genes bioRxiv (Cold Spring Harbor Laboratory) · 2020
    26. Fondation René Touraine Experimental Dermatology · 2013
    27. Editors' Picks Journal of Investigative Dermatology · 2010
    28. Constitutive Stat3 activation alters behavior of hair follicle stem and progenitor cell populations Molecular Carcinogenesis · 2013 · 23 citations
    29. Dissecting the bulge in hair regeneration Journal of Clinical Investigation · 2012 · 86 citations
    30. Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis Proceedings of the National Academy of Sciences · 2017 · 59 citations