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    Glossary Leucine-rich repeats and immunoglobulin-like domains protein 1

    protein regulating cell growth and maintaining stem cells

    Leucine-rich repeats and immunoglobulin-like domains protein 1 (Lrig1) is a protein that plays a crucial role in regulating cell growth and maintaining stem cell populations in various tissues, including the skin and hair follicles. It acts as a tumor suppressor and helps control the signaling pathways that can lead to cell proliferation, making it important for both normal tissue maintenance and cancer prevention.

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    Research 10 of 746

    1. 078 The transmembrane protein LRIG1 regulates receptor tyrosine kinases in skin development and homeostasis Journal of Investigative Dermatology · 2017
    2. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    3. Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing Frontiers in Medicine · 2022 · 5 citations
    4. Targeted protein degradation of Wnt/β-catenin signaling pathway: an effective strategy for cancer therapy Journal of Translational Medicine · 2025 · 8 citations
    5. 1371 FGF7-dependent inhibition of human hair growth byan osteopontin-derived peptide: A novel solution for hirsutism and hypertrichosis? Journal of Investigative Dermatology · 2018
    6. 1375 Cutaneous adnexal cysts revisited: A novel classification based on morphological and molecular features Journal of Investigative Dermatology · 2018
    7. S100A6: molecular function and biomarker role Biomarker Research · 2023 · 50 citations
    8. Expanding the Scope of PROTACs: Opportunities and Challenges in Topical Delivery Journal of Medicinal Chemistry · 2025
    9. An Intrinsic Oscillation of Gene Networks Inside Hair Follicle Stem Cells: An Additional Layer That Can Modulate Hair Stem Cell Activities Frontiers in Cell and Developmental Biology · 2020 · 23 citations
    10. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
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