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GlossaryLeucine-rich repeats and immunoglobulin-like domains protein 1

protein regulating cell growth and maintaining stem cells

Leucine-rich repeats and immunoglobulin-like domains protein 1 (Lrig1) is a protein that plays a crucial role in regulating cell growth and maintaining stem cell populations in various tissues, including the skin and hair follicles. It acts as a tumor suppressor and helps control the signaling pathways that can lead to cell proliferation, making it important for both normal tissue maintenance and cancer prevention.

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research Epithelial-Mesenchymal Interaction in Hair Regeneration and Skin Wound Healing

5 citations , April 2022 in “Frontiers in Medicine”

Hair and skin healing involve complex cell interactions controlled by specific molecules and pathways, and hair follicle cells can help repair skin wounds.

research Dermal White Adipose Tissue: Development and Impact on Hair Follicles, Skin Defense, and Fibrosis

3 citations , September 2024 in “The FASEB Journal”

Dermal white adipose tissue helps regulate hair growth, protect skin, and aid wound healing.

research Dynamic Signals for Hair Follicle Development and Regeneration

60 citations , July 2011 in “Stem Cells and Development”

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

research Specific In Vivo Ablation of Lrig1-Positive Follicular Progenitor Cells Results in Sebaceous Gland Loss in Mice

February 2026 in “International Journal of Molecular Sciences”

Removing Lrig1-positive cells in mice leads to temporary loss of sebaceous glands.

research Cutaneous Adnexal Cysts Revisited: A Novel Classification Based on Morphological and Molecular Features

April 2018 in “Journal of Investigative Dermatology”

The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.

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community Carnitine Tartrate + Potassium chloride + Niacin

8 upvotes 11 years ago

The post discusses using Carnitine Tartrate, Potassium Chloride, and Niacin to reduce hair shedding, with the user experiencing significant improvement. The user also suggests considering a ketogenic/paleo diet for those with insulin resistance-related hair loss.

community Indian Subcontinent specific : Fin effects

in Finasteride/Dutasteride 6 upvotes 5 years ago

Oral finasteride is recommended over topical finasteride for men in the Indian subcontinent, with no reported side effects. Minoxidil and dermarolling are also suggested, while dietary supplements and topical finasteride are deemed less effective.

community Is EAA good or bad for hair? I cant find Any information about it.

in Product 1 upvotes 4 years ago

The conversation is about whether an EAA supplement affects hair health. The user lists the ingredients but does not receive a definitive answer.

community DIY NutraKos-style 6–amino-acid mix (recipe + references)

in Product 1 upvotes 1 month ago

A user shared a DIY recipe for a NutraKos-style amino acid mix as a cost-effective alternative to the expensive product, suggesting it as a complementary supplement for hair loss. Another user argued that proven treatments like finasteride and minoxidil are more reliable, questioning the efficacy of the amino acid mix.

community 30M Experiencing Shedding After Restarting Min + Fin + Mesotherapy, Is It Too Late?

bloodyreptar in General 168 upvotes 4 months ago

A 30-year-old is seeking advice on hair loss treatment, currently using oral minoxidil, finasteride, mesotherapy, and a supplement. They are experiencing shedding and are anxious about the effectiveness of the treatment, asking if they should continue or consider other options like topicals or microneedling.