isoleucine

This case study of a 2-month-old boy with maple syrup urine disease highlights the dangers of restricting branched-chain amino acid intake, as it led to acrodermatitis dysmetabolica-like skin eruptions and hair loss, later resolved with careful dietary adjustments and monitoring.

This article discusses the functions of the enzyme 17beta-HSD10, including its role in steroid metabolism and potential links to Alzheimer's disease, but reports no new experimental findings.

This case study reports that an infant with maple syrup urine disease developed acrodermatitis dysmetabolica due to low isoleucine levels, and increasing the isoleucine dose improved the condition.

This review discusses the role of jasmonic acid and its conjugates in enhancing plant stress tolerance and balancing growth and defense mechanisms but provides no new experimental data.

This study suggests that the dipeptide Pro-Ile has FGF18-like activity, can penetrate model human epidermis, and may have potential as a cosmetic ingredient for skin and hair regulation.

The authors concluded that newly synthesized N-acyl-L-tryptophanyl-isoleucine amides showed high anxiolytic activity in animal models, comparable to diazepam, through interaction with the TSPO receptor.

This review highlights that Fenugreek seeds and leaves contain different bioactive compounds, with seeds showing anti-diabetic and anti-hyperlipidemic effects and leaves exhibiting strong anti-microbial properties. Both parts also provide anti-inflammatory benefits and support hair health, underscoring the potential for optimized therapeutic applications from Trigonella foenum-graecum.

This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.

The authors concluded that liver transplantation in children with propionic acidemia can reduce the risk of metabolic decompensation and enhance quality of life, although some metabolic issues may persist.

This review discusses the synthesis and biological activities of jasmonates, highlighting their potential as drugs and prodrugs, but reports no new clinical results; further research and trials are anticipated.

This case report describes a 10-month-old boy with dermatitis, alopecia, and hypotonia who showed dramatic improvement with oral biotin, suggesting a possible defect in biotin absorption or transport.

Hair fibers may have a unique, non-protein sheath not previously identified.

This review reports that Fenugreek seeds contain compounds like Galactomannan and Trigonelline, which show anti-diabetic and anti-hyperlipidemic effects, while Fenugreek leaves have high saponin content, contributing to their anti-microbial activities.

In this study, differences in protein expression related to twin lambing were identified in Tibetan sheep, providing insights into the reproductive performance and fertility improvement strategy for sheep in the Qinghai-Tibet Plateau.

This study found that a more liberal intake of restricted amino acids in patients with methylmalonic acidemia resulted in improved growth and fewer illness episodes.

In this study, L-methionine and L-serine application was observed to have the most significant effect on hair weight and root length, followed by acetyl L-methionine and L-serine, while glutathione inhibited growth.

This study found that the mammalian hairless gene encodes a corepressor protein that interacts with thyroid hormone receptors, providing insights into hair loss syndromes in humans and mice.

This review discusses the pharmacology and toxicology of cyclooxygenase in skin, highlighting its role in inflammation, wound healing, and tumorigenesis, without presenting new clinical results.

This review discusses how Western diet may contribute to acne vulgaris through insulin signaling and metabolomic changes, promoting a dietary approach for management, but reports no new experimental results.

This review discusses recent strategies targeting the neuroactive steroid biosynthetic pathway to enhance neurosteroidogenesis, highlighting their potential benefits for neurodegenerative and neuropsychiatric diseases, but reports no new clinical findings.