New Small Molecules in Dermatology: For Autoimmunity, Inflammation, and Beyond

    May 2023 in “ Inflammation Research ”
    Paulo Ricardo Criado, Daniel Lorenzini, Hélio Amante Miot … Mayra Ianhez
    Studysummary This study reported that new drugs, despite lower specificity compared to certain immunobiological therapies, are effective across various challenging dermatological diseases, such as psoriasis, psoriatic arthritis, atopic dermatitis, alopecia areata, and vitiligo.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 8

    1. The JAK/STAT Signaling Pathway: From Bench to Clinic Signal Transduction and Targeted Therapy · 2021
    2. Topical Tofacitinib for the Treatment of Alopecia Areata Affecting Facial Hair British Journal of Dermatology · 2021
    3. A Phase 2a Randomized, Placebo-Controlled Study to Evaluate the Efficacy and Safety of the Oral Janus Kinase Inhibitors Ritlecitinib and Brepocitinib in Alopecia Areata: 24-Week Results Journal of the American Academy of Dermatology · 2021
    4. Emerging Topical and Systemic JAK Inhibitors in Dermatology Frontiers in Immunology · 2019
    5. Tyrosine Kinases in Autoimmune and Inflammatory Skin Diseases Frontiers in immunology · 2019
    6. Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis Journal of the American Academy of Dermatology · 2018
    7. JAK Inhibitors in Dermatology: The Promise of a New Drug Class Journal of the American Academy of Dermatology · 2017
    8. Tyrosine Kinase Inhibitors: A Review on Pharmacology, Metabolism, and Side Effects Current drug metabolism · 2009

    Related research 2

    1. Treatment With Oral Janus Kinase Inhibitors in Adult Patients With Alopecia Areata: A Systematic Review and Meta-Analysis Journal of the American Academy of Dermatology · 2023
    2. Inhibiting Janus Kinases to Treat Alopecia Areata Nature medicine · 2014