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Research

5 / 1000+ results

research Alopecia areata is driven by cytotoxic T lymphocytes and is reversed by JAK inhibition

701 citations , August 2014 in “Nature medicine”

This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.

research The JAK/STAT signaling pathway: from bench to clinic

489 citations , November 2021 in “Signal Transduction and Targeted Therapy”

This review discusses the composition, activation, and regulation of the JAK/STAT pathway and highlights its role and inhibitors in various diseases, but reports no new experimental results.

research JAK inhibitors in dermatology: The promise of a new drug class

355 citations , January 2017 in “Journal of the American Academy of Dermatology”

This review reports no new results and highlights existing research suggesting JAK inhibitors may be effective in treating inflammatory skin conditions like alopecia areata, atopic dermatitis, psoriasis, and vitiligo.

research Emerging Topical and Systemic JAK Inhibitors in Dermatology

277 citations , December 2019 in “Frontiers in Immunology”

This review discusses the immunological basis and development of Janus kinase inhibitors for treating skin diseases and reports no new clinical findings.

research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis

223 citations , September 2018 in “Rheumatology”

This review examines clinical data on the efficacy and safety of JAK inhibitors used for immune-mediated conditions beyond rheumatoid arthritis, highlighting their potential therapeutic roles in various inflammatory diseases.

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Learn

3 / 801 results

learn Hair Transplant

How should I care for my hair after a hair transplant? Follow your doctor's aftercare instructions, avoid sun exposure, and use gentle shampoo.
What is the DHI hair transplant technique? DHI is a hair transplant technique that uses a pen for direct implantation without incisions.
How long does a transplant take? A hair transplant typically takes between 4 to 10 hours to complete.
All 5 questions on Hair Transplant →

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

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Community Join

5 / 50 results

community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

29 upvotes 2 months ago

Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

community can someone help me identify these pls

in Treatment 9 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community No idea what's causing my hair thinning

in Chat 2 upvotes 1 year ago

The user is experiencing diffuse hair thinning despite using finasteride and oral minoxidil, with no hairline recession or bald spots. Suggestions include checking for telogen effluvium, considering a JAK inhibitor for potential autoimmune issues, and conducting further tests to rule out other causes.

community DUPA - 20 YO - Non responder to everything

in Finasteride/Dutasteride 13 upvotes 2 years ago

A 20-year-old user experienced worsening hair loss despite using various treatments including topical and oral minoxidil, finasteride, and dutasteride. Other users suggested additional treatments like JAK inhibitors, RU58841, and lifestyle changes, but the user remains skeptical and frustrated.

community The Worst Hair Loss Condition You (MAY) have: LPP

48 upvotes 2 years ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

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Clinics

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All 12 clinic results →