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Bioinformatic Analysis of Gene Expression Data Reveals Src Family Protein Tyrosine Kinases as Key Players in Androgenetic Alopecia

research Bioinformatic Analysis of Gene Expression Data Reveals Src Family Protein Tyrosine Kinases as Key Players in Androgenetic Alopecia

June 2023 in “Frontiers in Medicine”

Protein tyrosine kinases are key in male pattern baldness, affecting skin structure, hair growth, and immune responses.

research MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling

118 citations, August 2010 in “Developmental Cell”

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

research Vitamin D Metabolism and Function in the Skin

185 citations, December 2011 in “Molecular and cellular endocrinology”

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

research Vitamin D and the Skin: Physiology and Pathophysiology

158 citations, August 2011 in “Reviews in endocrine and metabolic disorders”

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

research Targeting Smoothened for Therapeutic Gain

105 citations, April 2014 in “Trends in Pharmacological Sciences”

Targeting the Smoothened receptor shows promise for treating certain cancers.

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Community Join

5 / 6 results

community Do you guys think it’s possible to DIY HMI-115?

in Technology 8 upvotes 2 years ago

Hair loss discussion includes DIY HMI-115 and its high cost (20-30k per person). Minoxidil, finasteride, and RU58841 mentioned as treatments.

community Age 18 vs Age 25, the importance of starting early

in Progress Pictures 869 upvotes 2 weeks ago

An 18-year-old began using Finasteride and Topical Minoxidil for hair loss, later switching to Oral Minoxidil and Dutasteride by age 25. The conversation emphasizes early treatment, potential side effects, and differing opinions on medication effectiveness.

community How is there still no consensus on Topical Dutasteride in 2024?

in Finasteride/Dutasteride 147 upvotes 7 months ago

The conversation expresses frustration over the lack of clear evidence regarding the effectiveness and systemic impact of topical Dutasteride for hair loss treatment, despite years of discussion. People are criticized for not conducting proper research and for providing contradictory anecdotal claims.

community Does anyone here use everything except Fin

in Minoxidil 23 upvotes 1 year ago

The conversation is about hair loss treatments, specifically Minoxidil (Min) and Finasteride (Fin). The original poster is considering using Min and other treatments but is hesitant about Fin, while the responses vary, with some advocating for early use of Fin and others warning about potential side effects.

community Sublingual Minoxidil - Cure to Hairloss?

in Minoxidil 583 upvotes 1 year ago

The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

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