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Did you mean Hematopoietic Cell E-/L-Selectin Ligand?

GlossaryHematopoietic Cell E-/L-Selectin Ligand

molecule on blood-forming cells aiding their movement along vessels

Hematopoietic Cell E-/L-Selectin Ligand is a molecule found on the surface of blood-forming cells (hematopoietic cells) that helps these cells stick to and move along blood vessel walls. This interaction is crucial for the cells to travel to different parts of the body, especially during immune responses or when the body is repairing tissues.

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research Current Understanding of the Pathways Involved in Adult Stem and Progenitor Cell Migration for Tissue Homeostasis and Repair

24 citations, May 2016 in “Stem Cell Reviews and Reports”

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

research Gene Array Profiling and Immunomodulation Studies Define a Cell-Mediated Immune Response Underlying the Pathogenesis of Alopecia Areata in a Mouse Model and Humans

114 citations, August 2002 in “Journal of Investigative Dermatology”

Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.

Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity

research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity

20 citations, June 2010 in “Genes and Immunity”

Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.

research Hardwiring Stem Cell Communication Through Tissue Structure

82 citations, March 2016 in “Cell”

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

research Graft-Versus-Host Disease: Comprehensive Overview by the American Academy of Dermatology

58 citations, April 2012 in “Journal of the American Academy of Dermatology”

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

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community Painkillers May Block Minoxidil

in Research/Science 14 upvotes 4 months ago

Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.