Comparative Proteomic Analyses Using iTRAQ-Labeling Provides Insights Into Fiber Diversity in Sheep and Goats

    October 2017 in “ Journal of proteomics ”
    Yan Li, Guangxian Zhou, Rui Zhang … Xiaolong Wang
    Studysummary This study found that specific proteins associated with fiber structure, hair growth, and fatty acid synthesis, including the DSC2 gene, may influence wool and hair characteristics in sheep and goats.
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    Research cited in this study 10

    1. Wool Keratin-Associated Protein Genes in Sheep: A Review Genes · 2016
    2. Transcriptome Analysis Reveals Skin Lipid Metabolism Related to Wool Diameter in Sheep bioRxiv (Cold Spring Harbor Laboratory) · 2016
    3. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016
    4. A Homozygous Missense Variant in Type I Keratin KRT25 Causes Autosomal Recessive Woolly Hair Journal of Medical Genetics · 2015
    5. Influence of Feed Restriction on the Wool Proteome: A Combined iTRAQ and Fiber Structural Study Journal of proteomics · 2014
    6. Krtap11-1, A Hair Keratin-Associated Protein, As A Possible Crucial Element For The Physical Properties Of Hair Shafts Journal of Dermatological Science · 2014
    7. Characterization of Low Abundance Wool Proteins Through Novel Differential Extraction Techniques Electrophoresis · 2010
    8. Development of a DNA-Analytical Method for the Identification of Animal Hair Fibers in Textiles Textile Research Journal · 2009
    9. Characterization of the Exocuticle A-Layer Proteins of Wool Experimental Dermatology · 2007
    10. Characterization of the Lipid Composition at the Proximal Root Regions of Human Hair International Journal of Cosmetic Science · 2005