Comparative Proteomic Analyses Using iTRAQ-Labeling Provides Insights Into Fiber Diversity in Sheep and Goats

    October 2017 in “ Journal of proteomics ”
    Yan Li, Guangxian Zhou, Rui Zhang, Jiazhong Guo, Chao Li, Graeme B. Martin, Yulin Chen, Xiaolong Wang
    TLDR The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.
    The study used an iTRAQ-based proteomic approach to analyze 27 fiber samples from sheep and goats, identifying proteins that contribute to fiber diversity. Key proteins identified included keratin and keratin-associated proteins, as well as those related to hair growth and fatty acid synthesis. The DSC2 gene was highlighted as a significant determinant of woolly versus straight hair in goats. This research provided a valuable list of candidate proteins for future studies on the molecular mechanisms underlying fiber diversity in fiber-producing animals.
    Discuss this study in the Community →

    Research cited in this study

    10 / 10 results

    Related Community Posts Join

    6 / 159 results

      community Comprehensive Microneedling Guide

      in Microneedling  289 upvotes 3 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Keratin microspheres - breakthrough

      in Research/Science  14 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Results of Procyanidin B2 in clinical studies

      in Treatment  13 upvotes 5 years ago
      Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

      community Dec 2024 vs now (min + fin/dut)

      in Progress Pictures  27 upvotes 2 weeks ago
      The user experienced hair thickening and reduced shedding using minoxidil, finasteride, and dutasteride, with a switch from finasteride to dutasteride due to ineffectiveness. They also use a saw palmetto shampoo and take vitamin D3 supplements, while considering potential underlying causes like vitamin deficiencies and hard water buildup.

    Similar Research

    5 / 1000+ results