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GlossaryKeratin 6 (KRT6)

protein in skin, hair, and nails providing structural support

Keratin 6 (K6) is a type of protein found in the epithelial cells of the skin, hair, and nails. It plays a crucial role in the structural integrity and resilience of these tissues. Mutations in the KRT6 gene, which encodes Keratin 6, can lead to disorders such as pachyonychia congenita, characterized by thickened nails and other skin abnormalities.

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research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

Comparative Histomorphometric and Transcriptomic Analysis Reveals Potential Genetic Determinants of Pelage Variation Between Hairy and Coarse-Woolly Sheep

research Comparative Histomorphometric and Transcriptomic Analysis Reveals Potential Genetic Determinants of Pelage Variation Between Hairy and Coarse-Woolly Sheep

November 2025 in “BMC Genomics”

Genetic differences in sheep affect wool type, with fat and immune genes influencing hair traits.

research Genetic Variants in Pachyonychia Congenita-Associated Keratins Increase Susceptibility to Tooth Decay

21 citations , January 2018 in “PLoS Genetics”

Certain genetic variants in keratins increase the risk of tooth decay.

research Comparative Proteomic Analyses Using iTRAQ-Labeling Provides Insights Into Fiber Diversity in Sheep and Goats

29 citations , October 2017 in “Journal of proteomics”

The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

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community oral minoxidil is coming in clutch fr

in Satire 641 upvotes 3 years ago

. This conversation is a satire post about a user who appears to have an abundance of hair, with other users commenting and asking questions about the treatments they use for their hair loss. Treatments discussed include minoxidil and finasteride.