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GlossaryKeratin 6 (KRT6)

protein in skin, hair, and nails providing structural support

Keratin 6 (K6) is a type of protein found in the epithelial cells of the skin, hair, and nails. It plays a crucial role in the structural integrity and resilience of these tissues. Mutations in the KRT6 gene, which encodes Keratin 6, can lead to disorders such as pachyonychia congenita, characterized by thickened nails and other skin abnormalities.

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research Krt6a-Cre Transgenic Mice Direct LoxP-Mediated Recombination to the Companion Cell Layer of the Hair Follicle and Following Induction by Retinoic Acid to the Interfollicular Epidermis

10 citations , January 2004 in “Journal of Investigative Dermatology”

research Comparative Proteomic Analyses Using iTRAQ-Labeling Provides Insights Into Fiber Diversity in Sheep and Goats

29 citations , October 2017 in “Journal of proteomics”

The research found specific proteins that affect fiber characteristics and hair growth in sheep and goats.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research The Human Type II Keratin Gene Cluster on Chromosome 12q13.13: Final Count or Hidden Secrets?

9 citations , February 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

The document concludes that the human keratin gene cluster is complex, with a need for updated naming to reflect over 50 functional genes important for hair and skin biology.

research Keratin 17-Related Recessive Atypical Pachyonychia Congenita with Variable Hair and Tooth Anomalies

3 citations , June 2022 in “European journal of human genetics”

A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.

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in Satire 641 upvotes 3 years ago

. This conversation is a satire post about a user who appears to have an abundance of hair, with other users commenting and asking questions about the treatments they use for their hair loss. Treatments discussed include minoxidil and finasteride.