Skin Transcriptome Profiling of Changthangi Goats Highlights the Relevance of Genes Involved in Pashmina Production

    April 2020 in “ Scientific reports ”
    Sonika Ahlawat, Reena Arora, Rekha Sharma … R. K. Vijh
    Studysummary This study explored gene expression in Changthangi goats and found that higher expression of keratin-related genes and specific signaling pathways may play a role in the development of Pashmina fiber.
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    Research cited in this study 19

    1. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019
    2. Analyses of Histological and Transcriptome Differences in the Skin of Short-Hair and Long-Hair Rabbits BMC Genomics · 2019
    3. Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals Molecular Biology and Evolution · 2018
    4. The Inconsistent Regulation of HOXC13 on Different Keratins and the Regulation Mechanism on HOXC13 in Cashmere Goat (Capra Hircus) BMC Genomics · 2018
    5. A Comparison of Transcriptomic Patterns Measured in the Skin of Chinese Fine and Coarse Wool Sheep Breeds Scientific reports · 2017
    6. Skin Transcriptome Reveals the Intrinsic Molecular Mechanisms Underlying Hair Follicle Cycling in Cashmere Goats Under Natural and Shortened Photoperiod Conditions Scientific reports · 2017
    7. Wool Keratin-Associated Protein Genes in Sheep: A Review Genes · 2016
    8. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016
    9. Transcriptome Sequencing Reveals Differences Between Primary and Secondary Hair Follicle-Derived Dermal Papilla Cells of the Cashmere Goat PLoS ONE · 2013
    10. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
    11. Annotation of Sheep Keratin Intermediate Filament Genes and Their Patterns of Expression Experimental Dermatology · 2011
    12. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target During Hair Follicle and Nail Differentiation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2010
    13. Expression Patterns of Keratin Intermediate Filament and Keratin Associated Protein Genes in Wool Follicles Differentiation · 2009
    14. Peptidylarginine Deiminase Isoforms Are Differentially Expressed in Anagen Hair Follicles and Other Human Skin Appendages Journal of Investigative Dermatology · 2005
    15. Keratins of the Human Hair Follicle International review of cytology · 2005
    16. The RAIG Family Member, GPRC5D, Is Associated With Hard-Keratinized Structures ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2004
    17. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002
    18. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999
    19. Dynamic Expression Patterns of Tenascin, Proteoglycans, and Cell Adhesion Molecules During Human Hair Follicle Morphogenesis Developmental dynamics · 1994

    Related research 5

    1. Characterization and Expression Analysis of the Hair Keratin Associated Protein KAP26.1 British Journal of Dermatology · 2008
    2. Hair Follicle-Specific Keratins And Their Diseases Experimental cell research · 2007
    3. Keratins of the Human Hair Follicle International review of cytology · 2005
    4. Hair Follicle Differentiation And Regulation The International Journal of Developmental Biology · 2004
    5. Hair Keratin Pattern in Human Hair Follicles Grown In Vitro Experimental dermatology · 2003