Peptidylarginine Deiminase Isoforms Are Differentially Expressed in Anagen Hair Follicles and Other Human Skin Appendages

    Rachida Nachat, Marie‐Claire Méchin, Marie Charvéron … Michel Simon
    Studysummary This study demonstrates that PAD1 and PAD3 are involved in hair follicle differentiation, while PAD1 and PAD2 may play a role in the physiology of sweat glands and arrector pili muscles.
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    Research cited in this study 14

    1. Trichohyalin Mechanically Strengthens the Hair Follicle Journal of biological chemistry/˜The œJournal of biological chemistry · 2003
    2. K6irs1, K6irs2, K6irs3, And K6irs4 Represent The Inner-Root-Sheath-Specific Type II Epithelial Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2003
    3. Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles Journal of Investigative Dermatology · 2001
    4. Human Peptidylarginine Deiminase Type III: Molecular Cloning and Nucleotide Sequence of the cDNA, Properties of the Recombinant Enzyme, and Immunohistochemical Localization in Human Skin ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2000
    5. CLED: A Calcium-Linked Protein Associated With Early Epithelial Differentiation Experimental Cell Research · 2000
    6. Ultrastructural Localization of S100A3, a Cysteine-Rich, Calcium Binding Protein, in Human Scalp Hair Shafts Revealed by Rapid-Freezing Immunocytochemistry Journal of Histochemistry & Cytochemistry · 1999
    7. A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    8. The Fate of Trichohyalin Journal of biological chemistry/˜The œJournal of biological chemistry · 1997
    9. The Structure of Human Trichohyalin: Potential Multiple Roles as a Functional EF-Hand-Like Calcium-Binding Protein, a Cornified Cell Envelope Precursor, and an Intermediate Filament-Associated (Cross-Linking) Protein Journal of Biological Chemistry · 1993
    10. Analysis of the Sheep Trichohyalin Gene: Potential Structural and Calcium-Binding Roles of Trichohyalin in the Hair Follicle The Journal of Cell Biology · 1993
    11. Expression of Calcyclin, a Calcium-Binding Protein, in the Keratogenous Region of Growing Hair Follicles Journal of Investigative Dermatology · 1991
    12. Trichohyalin, an Intermediate Filament-Associated Protein of the Hair Follicle ˜The œjournal of cell biology/˜The œJournal of cell biology · 1986
    13. The Enzymic Derivation of Citrulline Residues from Arginine Residues In Situ During the Biosynthesis of Hair Proteins Cross-Linked by Isopeptide Bonds Advances in experimental medicine and biology · 1977
    14. The Localization And Significance Of Arginine And Citrulline In Proteins Of The Hair Follicle Journal of Histochemistry & Cytochemistry · 1963

    Related research 5

    1. TRPV3 Gain-of-Function Mutation Impairs Differentiation of Hair Follicle Inner Root Sheath ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2019
    2. Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2001
    3. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000
    4. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994
    5. Outer Root Sheath Keratinization in Anagen and Catagen of the Mammalian Hair Follicle: A Seventh Distinct Type of Keratinization in the Hair Follicle - Trichilemmal Keratinization PubMed · 1981