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GlossaryHenle's layer

outermost layer of the inner root sheath in hair follicles

Henle's layer, also known as Henle's sheath, is the outermost layer of the inner root sheath of a hair follicle. It plays a crucial role in supporting and protecting the growing hair shaft as it develops within the follicle.

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research A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle

86 citations, May 2002 in “Journal of Investigative Dermatology”

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

15 citations, July 2004 in “Journal of morphology”

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle

139 citations, December 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

K6hf is a unique protein found only in a specific layer of hair follicles.

research Integral Hair Lipid in Human Hair Follicle

36 citations, August 2011 in “Journal of dermatological science”

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.

research Staining of Human Skin With RGB Trichrome Unveils a Proteoglycan-Enriched Zone in the Hair Dermal Sheath

September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new staining method shows a special area in the hair's skin layer with lots of proteoglycans.

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community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning

in Finasteride/Dutasteride 6 upvotes 2 months ago

An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.

community Topical Dutasteride 0.1% and Dutasteride Mesotherapy 0.01% - 6 months

in Treatment 17 upvotes 2 years ago

Topical Dutasteride 0.05% twice a week and Dutasteride Mesotherapy 0.01% once a week showed noticeable improvement in hair loss over six months without side effects. The user plans to add Minoxidil tablets 2.5mg daily to their treatment.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 1 year ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community Why do I see so many people here recommend microneedling?

in Microneedling 110 upvotes 1 year ago

The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

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