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GlossaryHuxley layer

inner root sheath layer supporting hair shaft growth

The Huxley layer is a part of the inner root sheath of a hair follicle, situated between the Henle layer and the cuticle of the inner root sheath. It consists of several layers of flattened, nucleated cells that play a role in supporting and shaping the growing hair shaft.

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research A Novel Epithelial Keratin, hK6irs1, Is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells of the Human Hair Follicle

86 citations , May 2002 in “Journal of Investigative Dermatology”

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

research A Novel Type II Cytokeratin, mK6irs, Is Expressed in the Huxley and Henle Layers of the Mouse Inner Root Sheath

45 citations , March 2001 in “Journal of Investigative Dermatology”

A new protein, mK6irs, is found in specific hair layers and may help understand hair growth and diseases.

research K6irs1, K6irs2, K6irs3, And K6irs4 Represent The Inner-Root-Sheath-Specific Type II Epithelial Keratins Of The Human Hair Follicle

130 citations , April 2003 in “Journal of Investigative Dermatology”

Four specific keratins in hair follicles help understand hair structure and function.

research Premature Termination of Hair Follicle Morphogenesis and Accelerated Hair Follicle Cycling in Iasi Congenital Atrichia (fzica) Mice Points to Fuzzy as a Key Element of Hair Cycle Control

20 citations , July 2005 in “Experimental dermatology”

The fuzzy gene is crucial for controlling hair growth cycles.

Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

15 citations , July 2004 in “Journal of morphology”

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

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