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    Glossary HOXC13

    gene crucial for hair development and growth

    HOXC13 is a gene that plays a crucial role in the development and growth of hair. It belongs to the homeobox (HOX) gene family, which is involved in regulating the formation of body structures during early embryonic development. Mutations or disruptions in the HOXC13 gene can lead to hair growth disorders, such as alopecia or other hair abnormalities.

    Research 10 of 309

    1. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002 · 132 citations
    2. Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia Development · 2001 · 114 citations
    3. Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia The American Journal of Human Genetics · 2012 · 74 citations
    4. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    5. Evidence That the Satin Hair Mutant Gene Foxq1 Is among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 during Hair Follicle Differentiation 2006 · 65 citations
    6. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    7. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018 · 43 citations
    8. Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study Journal of Cutaneous Pathology · 2005 · 27 citations
    9. Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat 2012 · 22 citations
    10. The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus) BMC Genomics · 2018 · 17 citations
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