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    Glossary HOXC13

    gene crucial for hair development and growth

    HOXC13 is a gene that plays a crucial role in the development and growth of hair. It belongs to the homeobox (HOX) gene family, which is involved in regulating the formation of body structures during early embryonic development. Mutations or disruptions in the HOXC13 gene can lead to hair growth disorders, such as alopecia or other hair abnormalities.

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    Research 30 of 309

    1. HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression Journal of Biological Chemistry · 2002 · 132 citations
    2. Overexpression of Hoxc13 in differentiating keratinocytes results in downregulation of a novel hair keratin gene cluster and alopecia Development · 2001 · 114 citations
    3. Loss-of-Function Mutations in HOXC13 Cause Pure Hair and Nail Ectodermal Dysplasia The American Journal of Human Genetics · 2012 · 74 citations
    4. The Nude Mutant Gene Foxn1 Is a HOXC13 Regulatory Target during Hair Follicle and Nail Differentiation 2010 · 68 citations
    5. Evidence That the Satin Hair Mutant Gene Foxq1 Is among Multiple and Functionally Diverse Regulatory Targets for Hoxc13 during Hair Follicle Differentiation 2006 · 65 citations
    6. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    7. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018 · 43 citations
    8. Expression patterns of hair and epithelial keratins and transcription factors HOXC13, LEF1, and β‐catenin in a malignant pilomatricoma: a histological and immunohistochemical study Journal of Cutaneous Pathology · 2005 · 27 citations
    9. Hoxc13/β-catenin Correlation with Hair Follicle Activity in Cashmere Goat 2012 · 22 citations
    10. The inconsistent regulation of HOXC13 on different keratins and the regulation mechanism on HOXC13 in cashmere goat (Capra hircus) BMC Genomics · 2018 · 17 citations
    11. Hoxc13 Expression Pattern in Cashmere Goat Skin During Hair Follicle Development 2009 · 12 citations
    12. Structure and expression of the ovine Hoxc-13 gene Gene · 2003 · 12 citations
    13. Expression analysis of KAP9.2 and Hoxc13 genes during different cashmere growth stages by qRT-PCR method Molecular biology reports · 2014 · 9 citations
    14. Determination of Secondary Follicle Characteristics, Density, Activity, and Hoxc13 Expression Pattern of Hexi Cashmere Goats Breed ˜The œanatomical record · 2015 · 7 citations
    15. miR-129-5p Participates in Hair Follicle Growth by Targeting HOXC13 in Rabbit Genes · 2022 · 5 citations
    16. Hoxc13 and homologs of mammalian hair keratins are required for the cornification of nuptial pads in Xenopus frogs Communications Biology · 2026
    17. Hoxc13 polyglycine repeat gain-of-function drives mammalian integument evolution by altering targeted genes and interactions Research Square · 2026
    18. 1426 Deletion of hoxc13 in frogs reveals key steps in the molecular evolution of cornified skin appendages 2023
    19. Molecular Genetic Characteristics of the Hoxc13 Gene and Association Analysis of Wool Traits International journal of molecular sciences · 2024
    20. The HOXC13-controlled expression of early hair keratin genes in the human hair follicle does not involve TALE proteins MEIS and PREP as cofactors Archives of Dermatological Research · 2005 · 18 citations
    21. Pure Hair‐Nail Ectodermal Dysplasia: Expanding the HOXC13 Genotypic Spectrum Pediatric Dermatology · 2026
    22. Correlation Analysis of CXCL10, FOS, HOXC13, and WNT4 Gene Polymorphisms with Key Economic Traits—Initial Population Screening for Jiangnan Cashmere Goats Genes · 2025
    23. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations
    24. <i>Hoxc13</i> mutant mice lack external hair Genes & Development · 1998 · 245 citations
    25. Molecular biology of hair morphogenesis: Development and cycling Journal Of Experimental Zoology Part B: Molecular And Developmental Evolution · 2003 · 155 citations
    26. Dlx3 is a crucial regulator of hair follicle differentiation and cycling Development · 2008 · 132 citations
    27. Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation Experimental Cell Research · 1989 · 128 citations
    28. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    29. Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium Mechanisms of Development · 2004 · 56 citations
    30. Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression Journal of Cutaneous Pathology · 2014 · 47 citations