Expression Patterns of Keratin Intermediate Filament and Keratin Associated Protein Genes in Wool Follicles

    March 2009 in “ Differentiation ”
    Zhidong Yu, Steven W. Gordon, A. J. Nixon, C. Simon Bawden, Michael A. Rogers, Janet E. Wildermoth, Nauman J. Maqbool, A.J. Pearson
    TLDR Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.
    This study characterized the expression patterns of novel keratin intermediate filaments (KIFs) and keratin-associated proteins (KAPs) in wool follicles of New Zealand Wiltshire sheep, identifying full coding sequences for three new KIFs (KRT27, KRT35, and KRT38) and one KAP (KRTAP4-3). The research found that gene expression varied with the wool follicle growth cycle, becoming more restricted during regression and ceasing during dormancy, with differences noted between primary and secondary follicles. These findings provided insights into the molecular mechanisms of wool growth and structure, with potential implications for understanding similar processes in human hair.
    Discuss this study in the Community →

    Research cited in this study

    34 / 34 results

    Related Community Posts Join

    6 / 154 results

      community Keratin fibers vs. Gossypium Herbaceum Hair fibers

      in Product  1 upvotes 1 year ago
      The conversation is about comparing keratin hair fibers to Gossypium Herbaceum hair fibers for diffuse hair loss. The user prefers keratin fibers for their durability and is seeking a bulk purchase option.

      community Keratin microspheres - breakthrough

      in Research/Science  15 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Discussion: Keratin Microsphere Results

      in Treatment  31 upvotes 1 year ago
      Keratin microspheres may offer additional mechanisms to combat hair loss compared to minoxidil. The process to create these microspheres is relatively simple and can be done at home with basic equipment.

      community Let's talk keratin products and hair loss

      in Styling  2 upvotes 1 month ago
      OP is considering using a keratin gel to improve hair quality and is concerned about its safety and visual impact on a slightly balding crown. Users discuss shampoo frequency, with some suggesting less frequent use for better hair health, but OP prefers regular shampoo and conditioner for silky hair.

    Related Research

    7 / 7 results