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research Biology of the wool follicle: an excursion into a unique tissue interaction system waiting to be re‐discovered

117 citations , November 2006 in “Experimental Dermatology”

This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.

research Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep

112 citations , September 2021 in “BMC Biology”

This study found that specific gene expressions during different stages of hair follicle development in Merino sheep are linked to wool-related traits, and may also be relevant to human skin, metabolic, and immune traits.

research Expression patterns of keratin intermediate filament and keratin associated protein genes in wool follicles

95 citations , March 2009 in “Differentiation”

Gene expression in wool follicles changes with growth cycles, offering insights into wool and human hair growth.

research The Cytology and Cytochemistry of the Wool Follicle

90 citations , January 1979 in “International review of cytology”

This chapter reviews the complexity of hair and wool follicle formation, emphasizing the importance of cytological studies to understand the relationship between cellular components.

research Structure and expression of genes for a class of cysteine-rich proteins of the cuticle layers of differentiating wool and hair follicles.

67 citations , December 1990 in “The journal of cell biology/The Journal of cell biology”

This study identified two evolutionarily conserved ultra-high-sulfur keratin proteins in human and sheep hair follicles, which are specifically expressed in the hair cuticle during the late stages of fiber development.

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community Haircafe slams pp405 presentation. Are results really that bad?

64 upvotes 5 months ago

PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 11 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community A little more than a month using red light therapy. I'm surprised by the progress.

263 upvotes 5 months ago

Red light therapy has shown promising results in hair regrowth for the user, who avoids minoxidil and finasteride due to side effects. The user follows a healthy lifestyle with diet, exercise, and sauna use, and will continue monitoring the therapy's effectiveness.

community Claim: Insulin resistance increases the enzyme that creates DHT and affects the liver's ability to control hormones

in Research/Science 4 upvotes 11 months ago

Insulin resistance may increase DHT production, contributing to hair loss, and addressing it through diet, nutrients, and natural DHT blockers like saw palmetto and pumpkin seed oil could help reverse hair loss. Some users prefer medications like finasteride for more effective results.

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