Serum-Free Culture of Wool Follicles: Effects of Nutrients, Growth Factors, and Hormones

    October 1997 in “ British Journal of Dermatology ”
    E J Bates, PI Hynd, Natalie M. Penn, M J Nancarrow
    Studysummary This study found that a serum-free culture system supported hair growth from follicles responsive to calcium, glucose, and amino acids, with insulin enhancing the growth, while other factors had no effect.
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    Research cited in this study 11

    1. Inhibition of Polyamine Synthesis Alters Hair Follicle Function and Fiber Composition Journal of Investigative Dermatology · 1996
    2. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995
    3. Transfection of Rat Dermal Papilla Cells with a Gene Encoding a Temperature-Sensitive Polyomavirus Large T Antigen Generates Cell Lines Retaining a Differentiated Phenotype Journal of Cell Science · 1994
    4. Growth of Wool Follicles in Culture In vitro cellular & developmental biology. Animal · 1994
    5. Prolonged Maintenance of Human Hair Follicles In Vitro in a Serum-Free Medium British Journal of Dermatology · 1993
    6. Soluble Factors From Human Hair Papilla Cells And Dermal Fibroblasts Dramatically Increase The Clonal Growth Of Outer Root Sheath Cells Archives of Dermatological Research · 1993
    7. Metabolism of Freshly Isolated Human Hair Follicles Capable of Hair Elongation: A Glutaminolytic, Aerobic Glycolytic Tissue Journal of Investigative Dermatology · 1993
    8. Rat Hair Follicle Growth In Vitro British Journal of Dermatology · 1992
    9. Inductive Properties of Hair Follicle Cells Annals of the New York Academy of Sciences · 1991
    10. Isolation, Culture, and In Vitro Behavior of Cells Isolated from Papillae of Human Hair Follicles 1989
    11. Glucose and Acetate Metabolism by Isolated Sheep Wool Follicles Archives of biochemistry and biophysics · 1965

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