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Glossary Pigmentation

natural coloring of tissues due to pigments like melanin

Pigmentation refers to the natural coloring of an organism's tissues, primarily due to the presence of pigments like melanin in the skin, hair, and eyes. In humans, variations in pigmentation are responsible for different skin tones and hair colors, and changes in pigmentation can be indicative of certain medical conditions or genetic factors.

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Research

5 / 1000+ results

research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes

13 citations , March 2020 in “Frontiers in cell and developmental biology”

This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.

research Predicting hair cortisol levels with hair pigmentation genes: a possible hair pigmentation bias

23 citations , August 2017 in “Scientific Reports”

Darker hair may lead to higher cortisol readings, suggesting a need to adjust for hair color in studies.

research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination

2 citations , April 2025 in “Frontiers in Genetics”

This study investigated the genetic basis of coat color variation in cattle using skin transcriptome and whole-genome analyses, identifying the ASIP gene as a significant determinant that is differentially expressed and under strong positive selection in black and brown cattle breeds.

research Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes

3 citations , February 2025 in “Journal of PHYSIOLOGICAL ANTHROPOLOGY”

This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.

research Genetic Basis of Pigmentation and Its Disorders

7 citations , December 1981 in “International Journal of Dermatology”

Understanding genes can help diagnose and treat skin color disorders.

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Learn

5 / 801 results

learn Scalp Micropigmentation

How much does scalp micropigmentation cost? Scalp micropigmentation typically costs between $1,000 and $5,000 depending on individual needs.
Will scalp micropigmentation damage my existing hair or follicles? Scalp micropigmentation does not damage existing hair or follicles.
Does scalp micropigmentation hurt? Scalp micropigmentation typically causes minimal discomfort, often described as light scratching.
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learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Stem Cell Factor

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Overview

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Community Join

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community What is this pigmentation around my follicles?

in Chat 29 upvotes 1 year ago

The conversation discusses potential causes of pigmentation around hair follicles, suggesting sebum buildup, autoimmune conditions, or dermatitis. Treatments mentioned include finasteride, dutasteride, and an anti-inflammatory diet, with a recommendation to consult a doctor for a proper diagnosis.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 1 year ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community Has anyone done research on Absci's AI‑driven antibody platform? Seeking your thoughts!

4 upvotes 1 year ago

A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.

community 1 year progress. That's why i say consistency is key.

in Progress Pictures 312 upvotes 1 year ago

The user experienced significant hair regrowth after resuming treatment with oral minoxidil and dutasteride, following an initial period of using finasteride and minoxidil. They noted improvements in hair density and pigmentation, attributing the progress to consistent use of these treatments.

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Clinics

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Experts

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22
Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi