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    Glossary Fibroblast Growth Factor 5

    protein that inhibits hair growth by signaling phase transition

    Fibroblast Growth Factor 5 (FGF5) is a protein that plays a crucial role in regulating the hair growth cycle. Specifically, it acts to inhibit hair growth by signaling the transition from the growth phase (anagen) to the regression phase (catagen), which can lead to shorter hair growth periods and potentially contribute to conditions like alopecia.

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    1. Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats Journal of Heredity · 2007 · 75 citations
    2. Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats Gene · 2015 · 42 citations
    3. CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen Genes · 2020 · 13 citations
    4. A homozygous missense mutation in the fibroblast growth factor 5 gene is associated with the long-hair trait in Angora rabbits BMC genomics · 2023 · 5 citations
    5. Effect of cysteine‐free human fibroblast growth factor‐5s mutant ( FGF5sC93S ) on hair growth Dermatologic Therapy · 2020 · 5 citations
    6. Identification of a Novel Missense Mutation in the Fibroblast Growth Factor 5 Gene Associated with Longhair in the Maine Coon Cat Research Square (Research Square) · 2021 · 2 citations
    7. Effect of iontophoresis with growth factor cocktail containing fibroblast growth factor 5-short applied to the scalp in patients with androgenetic alopecia – A split study Global dermatology · 2020
    8. Therapeutic effects of growth factor cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) in patients with androgenetic alopecia: A split study Global dermatology · 2020
    9. FC 2-2 : Therapeutic Effects of Growth Factor Cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) applied on the scalp in the patients with androgenetic alopecia: a split study 프로그램북(구 초록집) · 2020
    10. Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial Cosmetics · 2025
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