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    GlossaryWnt expression

    activity of genes crucial for cell signaling and hair growth

    Wnt expression refers to the activity of a group of genes known as Wnt genes, which produce proteins that play a crucial role in cell signaling pathways. These pathways are essential for regulating cell growth, development, and differentiation, including the growth of hair follicles. In the context of hair biology, proper Wnt expression is necessary for the normal cycling and regeneration of hair.

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      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

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      signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

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      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  93 upvotes 3 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Just received my 2 Deoxy D Ribose wish me luck🫡

      in Treatment  247 upvotes 1 year ago
      A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  51 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.