This study reports that in Rex rabbits, age affects fur quality and hair follicle traits, with the Wnt signaling pathway playing a role in their periodic hair follicle development.
June 2010 in “Seoul National University Open Repository (Seoul National University)” This article discusses the expression of vitamin D receptor in hair follicles and its role in alopecia, without presenting new findings; the authors highlight the involvement of Wnt/b-catenin signaling in hair growth.
In this study, researchers performed a genome-wide characterization of the Wnt gene family in domestic donkeys, identifying 19 genes and highlighting their evolutionary conservation among mammals, along with tissue-specific expression patterns potentially linked to reproductive regulation and tissue homeostasis.
17 citations
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September 2020 in “Inflammation and Regeneration” In this study, researchers found that WNT activation influenced FGF expression in human scalp-derived fibroblasts, with mouse model results showing FGF9 increased hair follicle number and diameter, while FGF7 reduced diameter.
6 citations
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November 2023 in “Experimental Dermatology” This study found that biglycan, a protein secreted by dermal papilla cells, plays a critical role in hair follicle cycle regulation and regeneration in mice by activating the Wnt/β-catenin signalling pathway, suggesting its potential as a treatment target for hair loss.