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    GlossaryWnt proteins

    regulate cell growth and development through signaling pathways

    Wnt proteins are a group of signaling molecules that play a crucial role in regulating cell-to-cell interactions during embryogenesis and in adult tissues. They are essential for processes like cell proliferation, migration, and differentiation, and are particularly important in the development and maintenance of hair follicles.

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      learn KY19382

      compound that activates Wnt/β-catenin to promote hair regrowth and create new hair follicles

      learn Estradiol

      an estrogen promoting hair regrowth more commonly used in women

      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

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      community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

      in Research/Science  92 upvotes 2 years ago
      The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

      community Better Than Minoxidil? Topical Sodium Valproate

      in Research/Science  53 upvotes 2 months ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.