Wnt/β-Catenin Pathway in Tissue Injury: Roles in Pathology and Therapeutic Opportunities for Regeneration

June 2016 in “ The FASEB Journal ”

Dikshya Bastakoty, Pampee P. Young

Wnt/β-catenin signaling pathway fibrosis stem cell maintenance organ homeostasis pharmacologic Wnt inhibition small-molecule Wnt inhibitors regenerative medicine

Studysummary This review discusses the dual role of the Wnt/β-catenin pathway in mammalian tissue injury, highlighting its potential for both promoting regeneration and contributing to fibrosis, but presents no new findings.

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