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    Did you mean Small Molecule Inhibitor?
    Glossary Small Molecule Inhibitor

    blocks specific proteins or enzymes within cells

    A Small Molecule Inhibitor (SMI) is a type of drug that can enter cells easily due to its low molecular weight and can interfere with specific proteins or enzymes to block their activity. These inhibitors are often used in treatments for various diseases, including cancer and autoimmune disorders, by targeting and disrupting specific pathways that contribute to disease progression.

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    Research 10 of 1000+

    1. 711 Small molecule wnt pathway inhibitor (SM04755) as a potential topical psoriasis treatment Journal of Investigative Dermatology · 2017
    2. High-throughput screening of small molecule Wnt/β-catenin activators for hair and nail growth Communications Biology · 2026
    3. Wnt/β‐catenin pathway in tissue injury: roles in pathology and therapeutic opportunities for regeneration The FASEB Journal · 2016 · 94 citations
    4. Targeting the Wnt pathways for therapies Molecular and cellular therapies · 2014 · 112 citations
    5. The roles of Wnt/β‐catenin pathway in tissue development and regenerative medicine Journal of Cellular Physiology · 2017 · 89 citations
    6. High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth Research Square (Research Square) · 2024
    7. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025
    8. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012 · 85 citations
    9. Inhibition of Wnt/β‐catenin pathway promotes regenerative repair of cutaneous and cartilage injury The FASEB Journal · 2015 · 41 citations
    10. The Effect of JAK Inhibitor on the Survival, Anagen Re-Entry, and Hair Follicle Immune Privilege Restoration in Human Dermal Papilla Cells International Journal of Molecular Sciences · 2020 · 16 citations
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