Role of the Wnt Signaling Pathway in Keratoacanthoma

    November 2019 in “ Cancer reports ”
    Sarita Joshi, Paula M. De Angelis, Manuela Zucknick … O. P. F. Clausen
    Studysummary This study concluded that the Wnt signaling pathway does not significantly influence human keratoacanthoma development, but the overexpression of Sox9 suggests alternate signaling involvement.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 5

    1. Spontaneous Tumor Regression in Keratoacanthomas Is Driven by Wnt/Retinoic Acid Signaling Cross-Talk Nature Communications · 2014
    2. The Changes in the Expression Levels of Follicular Markers in Keratoacanthoma Depend on the Stage: Keratoacanthoma Is a Follicular Neoplasm Exhibiting Infundibular/Isthmic Differentiation Without Expression of CK15 Journal of Cutaneous Pathology · 2014
    3. Differential Sensitivity of Epidermal Cell Subpopulations to Beta-Catenin-Induced Ectopic Hair Follicle Formation Developmental Biology · 2010
    4. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    5. Multiple Roles for Activated LEF/TCF Transcription Complexes During Hair Follicle Development and Differentiation Development · 1999