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GlossarySOX9

gene crucial for hair follicle development and maintenance

SOX9 is a gene that plays a crucial role in the development and maintenance of various tissues, including hair follicles. It encodes a transcription factor that helps regulate the expression of other genes involved in cell differentiation and proliferation. In the context of hair biology, SOX9 is essential for the proper formation and cycling of hair follicles, and its dysfunction can contribute to conditions like alopecia.

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research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision Between Stem Cell Maintenance and Differentiation

research Differential Expression Levels of Sox9 in Early Neocortical Radial Glial Cells Regulate the Decision Between Stem Cell Maintenance and Differentiation

1 citations , December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)”

Sox9 levels in brain stem cells affect whether they stay as stem cells or become neurons.

research Congenital Generalized Hypertrichosis With a Copy Number Variation on Chromosome 17q24

April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.

research ERG Induces Androgen Receptor-Mediated Regulation of SOX9 in Prostate Cancer

224 citations , February 2013 in “The Journal of clinical investigation/The journal of clinical investigation”

ERG increases SOX9, promoting prostate cancer growth and invasion.

research Hair Follicle Stem Cells: A New Arena

1 citations , January 2011 in “International Journal of Trichology”

Hair follicle stem cells have significant potential for treating various disorders.

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community How Veradermics secured a total of $220 million in series B and C financing for oral minoxidil, I will never understand.....

in Chat 38 upvotes 4 months ago

Veradermics' oral minoxidil shows promise for hair regrowth, with some users reporting significant improvements, while Pelage's PP405 results are less convincing and lack transparency. There is skepticism about both treatments' long-term effectiveness and potential side effects.