Therapeutic Potential of Stem Cell-Derived Exosomes in Hair Regeneration: A Systematic Review

    July 2025 in “ World Journal of Stem Cells
    Neil Poddar, Adarsh Aratikatla, Ashim Gupta
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    TLDR Stem cell-derived exosomes could be a promising new treatment for hair regrowth.
    This systematic review examines the potential of stem cell-derived exosomes in hair regeneration, highlighting their ability to promote hair growth through various biological pathways. Studies show that exosomes can enhance hair regrowth by activating pathways like Wnt/β-catenin and PI3K/AKT, reducing apoptosis, and improving follicle health. Notable findings include the use of exosomes from adipose-derived stem cells, which resulted in denser hair regrowth and increased angiogenesis, and exosomes from human hair follicle stem cells, which reversed DHT-induced miniaturization. These results suggest that exosomes could serve as a promising alternative to traditional hair loss treatments.
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      in Microneedling  2 upvotes 3 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

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      in Research/Science  5 upvotes 1 year ago
      Exosome hair therapy involves injecting stem cell-derived exosomes into the scalp to boost hair follicle regeneration and repair. Exosomes, which are not stem cells but products of them, contain bioactive chemicals and specific growth factors that promote new blood vessel formation, increase cell proliferation, reduce inflammation, and improve tissue repair, all crucial for hair health.

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      in Hair Systems  8 upvotes 3 months ago
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