Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway

March 2023 in “ International Journal of Molecular Sciences ”

Yunxiao Liang, Xin Tang, Xue Zhang, Cuixiang Cao, Miao Yu, Miaojian Wan

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26 / 26 results

research Different Levels of EGF, VEGF, IL-6, MCP-1, MCP-3, IP-10, Eotaxin, and MIP-1α in the Adipose-Derived Stem Cell Secretome in Androgenetic Alopecia

1 citations , February 2022 in “Experimental Dermatology”

Certain proteins are found at higher levels in balding areas compared to non-balding areas, suggesting a link to hair loss. This could be useful for diagnosing and treating hair loss.

research Dermal Papilla Cell-Derived Extracellular Vesicles Increase Hair Inductive Gene Expression in Adipose Stem Cells via β-Catenin Activation

12 citations , January 2022 in “Cells”

Dermal papilla cell vesicles can boost hair growth genes in fat stem cells.

research Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics

17 citations , November 2021 in “Journal of Cosmetic Dermatology”

research Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells

5 citations , October 2021 in “PubMed”

Exosomes from human fat stem cells can potentially enhance hair growth and survival, providing a new possible treatment for hair loss.

research Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration

19 citations , June 2021 in “Tissue Engineering and Regenerative Medicine”

Fat stem cell particles help regrow hair.

research Exosomes Derived from Fisetin-Treated Keratinocytes Mediate Hair Growth Promotion

9 citations , June 2021 in “Nutrients”

Fisetin in fruits and vegetables helps hair growth in mice.

research The Novel Mechanisms and Applications of Exosomes in Dermatology and Cutaneous Medical Aesthetics

47 citations , April 2021 in “Pharmacological research”

Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.

research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia

23 citations , January 2021 in “Biomedicine & Pharmacotherapy”

DHT stops hair regrowth in mice, similar to human hair loss.

research MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

18 citations , December 2020 in “Frontiers in cell and developmental biology”

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

research Current Advances in Stem Cell-Based Therapies for Hair Regeneration

32 citations , August 2020 in “European Journal of Pharmacology”

Stem cell therapies show promise for hair regrowth but face production and application challenges.

research A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia

25 citations , August 2020 in “Stem Cells Translational Medicine”

ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.

research Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling

65 citations , July 2020 in “Science Advances”

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

research Stromal Vascular Fraction-Enriched Platelet-Rich Plasma Therapy Reverses the Effects of Androgenetic Alopecia

20 citations , May 2020 in “Journal of Cosmetic Dermatology”

SVF-PRP therapy effectively reverses hair loss effects.

research Autologous Micrografts from Scalp Tissue: Trichoscopic and Long-Term Clinical Evaluation in Male and Female Androgenetic Alopecia

41 citations , January 2020 in “BioMed Research International”

Micrografts improve hair density and thickness without side effects.

research Dihydrotestosterone Regulates Hair Growth Through the Wnt/β-Catenin Pathway in C57BL/6 Mice and In Vitro Organ Culture

23 citations , January 2020 in “Frontiers in Pharmacology”

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

research Autologous Cellular Method Using Micrografts of Human Adipose Tissue Derived Follicle Stem Cells in Androgenic Alopecia

88 citations , July 2019 in “International Journal of Molecular Sciences”

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations , January 2019 in “International journal of biological sciences”

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells

87 citations , June 2018 in “Biochemical and Biophysical Research Communications”

Exosomes from dermal papilla cells can help grow hair and might treat hair loss.

research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways

27 citations , October 2017 in “British Journal of Dermatology”

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

research The Impact of Oxidative Stress on Hair

59 citations , November 2015 in “International Journal of Cosmetic Science”

Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.

research Hair Restoration Surgery: Challenges and Solutions

31 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

1 / 1 results

research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway

March 2023 in “International Journal of Molecular Sciences”