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Did you mean Adipose-Derived Mesenchymal Stromal Cells?

GlossaryAdipose-Derived Stem Cells

stem cells harvested from fat tissue for regenerative purposes

Adipose-Derived Stem Cells (ADSCs) are stem cells that are harvested from fat tissue. These cells have the ability to differentiate into various cell types, including bone, cartilage, and muscle cells, making them valuable for regenerative medicine and tissue engineering. They are also being researched for their potential in treating conditions like alopecia, as they can promote hair growth and repair damaged hair follicles.

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research Adipose Mesenchymal Stromal Cell-Derived Exosomes Carrying MiR-122-5p Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicles by Targeting the TGF-β1/SMAD3 Signaling Pathway

March 2023 in “International Journal of Molecular Sciences”

ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.

Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

research Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures

May 2023 in “Cytotherapy”

Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.

research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-Conditioning

320 citations, December 2018 in “Frontiers in Immunology”

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

research Stem Cell-Derived Exosomes: Emerging Therapeutic Opportunities for Wound Healing

28 citations, April 2023 in “Stem cell research & therapy”

Tiny vesicles from stem cells could be a new treatment for healing wounds.

research Therapeutic Values of Exosomes in Cosmetics, Skin Care, Tissue Regeneration, and Dermatological Diseases

6 citations, April 2023 in “Cosmetics”

Exosomes could be effective for improving skin health and treating skin diseases.

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community Anyone Try Microneedling with Exosomes/AAPE?

in Microneedling 2 upvotes 2 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

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