Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling

    July 2020 in “ Science Advances
    Shiqi Hu, Zhenhua Li, Halle Lutz, Ke Huang, Teng Su, Jhon Cores, Phuong-Uyen Dinh, Ke Cheng
    Image of study
    TLDR Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
    A study from 2 years ago found that dermal exosomes containing miR-218-5p can promote hair regeneration in mice by regulating β-catenin signaling, indicating a potential therapeutic approach for hair loss. The exosomes increased hair growth and thickness, promoted hair follicle stem cell proliferation, and inhibited apoptosis, making miR-218-5p a potential therapeutic target for hair loss. Further research is needed to fully understand this process and determine if the same results can be replicated in humans.
    Discuss this study in the Community →

    Research cited in this study

    34 / 34 results

    Related Community Posts Join

    6 / 1000+ results

      community Anyone Try Microneedling with Exosomes/AAPE?

      in Microneedling  2 upvotes 2 years ago
      User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

      community How is no one talking about this?

      in Treatment  6 upvotes 2 weeks ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.
      [object Object]

      community After Exosomes Treatment.

       15 upvotes 5 years ago
      A user who underwent exosomes treatment for hair loss and reported their experience, with other users discussing the procedure and offering advice. They discussed options such as finasteride, minoxidil, RU58841 and hair transplants.

    Related Research

    8 / 8 results