Targeting JAK/STAT and Wnt/Beta-Catenin Pathways and 5-Alpha-Reductase Activity to Develop an Effective Anti-Hair Loss Product
November 2022
in “
Journal of Investigative Dermatology
”
JAK/STAT pathway Wnt/b-catenin pathway 5a-reductase Nasturtium officinale Tropaeolum majus Garcinia Mangostana Glyceryl laurate hair follicle dermal papilla cells outer root sheath keratinocytes testosterone DHT anagen hairs telogen hairs anagen/telogen ratio watercress Indian cress mangosteen Dihydrotestosterone
Studysummary This study found that a lotion containing specific plant extracts significantly increased the number of anagen hairs and the anagen/telogen ratio in subjects with androgenetic alopecia after three months of use.
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