85 citations
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February 1989 in “Journal of The American Academy of Dermatology”
This case report describes a newly identified condition called loose anagenhair of childhood, characterized by easily pluckable hair in two young boys, with variable duration and no scalp inflammation or scarring.
78 citations
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February 2004 in “British Journal of Dermatology”
This article reviews the potential impact of melatonin on hair growth, noting its benefits observed in animals, but reports no clinical results in humans to date.
This study suggests that chemotherapy-induced anagen effluvium represents patterned hair loss, with most patients retaining hairlines, but patterns do not vary significantly by age, symptoms, or chemotherapy type.
This study found that a dietary supplement containing L-cystine, medicinal yeast, and pantothenic acid significantly improved hair growth in women with telogen effluvium over six months compared to placebo.
Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.
A company is developing a topical dutasteride that targets hair follicles without significantly affecting systemic DHT levels, with trials underway to measure its effectiveness. Users discuss the potential benefits and skepticism around the formulation compared to existing treatments.
Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.
The conversation discusses interest in smooth release minoxidil and precision dutasteride for hair loss. A user mentions using an expensive shampoo recommended by their hair transplant surgeon.
KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.
Does caffeine stimulate hair growth or only slow hair loss?Caffeine stimulates hair follicles in laboratory cultures, and one open-label, manufacturer-funded trial in 210 men found a 0.2% caffeine topical non-inferior to minoxidil 5% on an anagen-ratio endpoint. A 2025 systematic review found only a few small controlled trials, mostly rated low or very low quality, and none in alopecia areata.
How does latanoprost work to make eyelashes and possibly scalp hair grow?Studies report that latanoprost, a prostaglandin analog, lengthens the anagen (growth) phase of hair follicles, which is the mechanism given for the eyelash thickening seen in glaucoma patients; on the scalp the evidence is one 16-man pilot study and animal work, so the effect there is unproven.