Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies

    Maria João Gomes, Susana Martins, Domingos Ferreira … Salette Reis
    Studysummary This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.
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    Research cited in this study 5

    1. Solid Lipid Nanoparticles Suspension Versus Commercial Solutions for Dermal Delivery of Minoxidil International Journal of Pharmaceutics · 2011
    2. In Vitro Skin Permeation of Monoolein Nanoparticles Containing Hydroxypropyl β-Cyclodextrin/Minoxidil Complex International Journal of Pharmaceutics · 2010
    3. Targeting to the Hair Follicles: Current Status and Potential Journal of dermatological science · 2010
    4. Male Pattern Baldness: Current Treatments, Future Prospects Drug Discovery Today · 2008
    5. Enhancement of Follicular Delivery of Finasteride by Liposomes and Niosomes International Journal of Pharmaceutics · 2006