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Glossary Zeta Potential

measure of particle surface charge in a liquid

Zeta potential is a measure of the electrical charge on the surface of particles in a liquid, which affects how they interact with each other. For example, in hair care products, understanding zeta potential can help in formulating shampoos and conditioners that prevent hair from clumping together, ensuring smoother and more manageable hair.

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research Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery

268 citations , April 2009 in “International Journal of Pharmaceutics”

In this study, niosomal formulations enhanced minoxidil skin accumulation compared to commercial and control solutions, suggesting a potential improvement for topical delivery in hair loss treatment.

research Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles

47 citations , July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics”

This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.

Development and Optimization of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability

research Development and Optimisation of Spironolactone Nanoparticles for Enhanced Dissolution Rates and Stability

38 citations , November 2016 in “Aaps Pharmscitech”

This study found that the nanostructured lipid carrier formulation with a 70:30 solid to liquid lipid ratio significantly increased the dissolution rate, entrapment efficiency, and stability of spironolactone compared to its raw form.

Lipid Nanoparticles for Topical and Transdermal Application for Alopecia Treatment: Development, Physicochemical Characterization, and In Vitro Release and Penetration Studies

research Lipid nanoparticles for topical and transdermal application for alopecia treatment: development, physicochemical characterization, and in vitro release and penetration studies

28 citations , March 2014 in “International Journal of Nanomedicine”

This study developed lipid nanoparticles for delivering minoxidil and finasteride to the dermis and hair follicles, showing stability and a desired prolonged release, though with low skin penetration levels.

research Enhanced skin permeation of 5α-reductase inhibitors entrapped into surface-modified liquid crystalline nanoparticles

16 citations , August 2014 in “Archives of Pharmacal Research”

This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.

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