Potential of Colostrum-Derived Exosomes for Promoting Hair Regeneration Through the Transition from Telogen to Anagen Phase

    Hyo-Suk Kim, Yeongji Jang, Eun Kyung Kim, Hochung Jang, Ha-Eun Cho, Geonhee Han, Hyun Kyu Song, Sun Yeou Kim, Yoosoo Yang
    TLDR Colostrum-derived exosomes can promote hair growth and may be a promising treatment for hair loss.
    The study investigates the potential of colostrum-derived exosomes (Milk-exo) for promoting hair regeneration by transitioning hair follicles from the telogen to anagen phase. Milk-exo was found to induce the proliferation of dermal papilla (DP) cells, crucial for hair growth, and counteract the inhibitory effects of dihydrotestosterone (DHT) on these cells. In vivo experiments on C57BL/6 mice showed that Milk-exo significantly improved hair growth, evidenced by increased β-catenin expression in hair follicles. The findings suggest that Milk-exo could offer a promising, less-invasive treatment for hair loss with minimal adverse effects.
    Discuss this study in the Community →

    Research cited in this study

    18 / 18 results

    Related Community Posts Join

    6 / 10 results

      community How is no one talking about this?

      in Treatment  6 upvotes 2 weeks ago
      Bovine colostrum is being discussed for its potential in hair regeneration, with some users noting that oral consumption may not be effective due to stomach acid destroying exosomes. The conversation also touches on ethical concerns about sourcing colostrum.
      [object Object]

      community Fin+Colostrum: My journey is a little different.

      in Is this regrowth?  14 upvotes 1 month ago
      The user has been using finasteride for 30 years and recently added colostrum to their routine, noticing darker hair regrowth. They experienced shedding with minoxidil and advise against its use, while highlighting the benefits and side effects of long-term finasteride use.

      community Finasteride/ Dut dosage advice

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      A 33-year-old user is seeking advice on adjusting their hair loss treatment, which includes daily finasteride, oral minoxidil, and various supplements. They are considering switching to alternate-day dosing of finasteride or dutasteride and are concerned about potential shedding and effectiveness.

      community Doing nuclear stack. Is there anything else I could do?

      in Treatment  6 upvotes 1 month ago
      The conversation discusses a comprehensive hair regrowth regimen including Dutasteride, Finasteride, microneedling, RU58841, oral and topical Minoxidil, Tretinoin, and Vitamin D3. Suggestions include dropping Finasteride, increasing Dutasteride, and considering additional treatments like caffeine, melatonin, and laser therapy, while emphasizing the effectiveness of Dutasteride and Minoxidil.

    Related Research

    8 / 8 results